Protein production · Europe · Research use only
From sequence to purified protein in 21 working days.
We express and purify proteins, antibodies and enzymes at small scale — so your team does not have to. Send a sequence, get tens of milligrams of purified material back, at R&D prices, from a lab inside the EU.
E. coli and CHO · cultures up to 10 L · low endotoxin as standard on bacterial batches, measured and reported
21working days
Sequence to purified protein, E. coli
1litre
Screening culture, tens of milligrams
10litres
Maximum culture scale
EU
Produced and shipped inside Europe
Two routes
Pick the system that fits the molecule, not the one we happen to run.
Most targets have an obvious home. If yours does not, tell us what it is and we will recommend a route before you pay anything — including recommending against us, if that is the honest answer.
Route 01
E. coli expression
The fast answer. A 1 L culture tells you whether your design folds, expresses and binds — before anyone commits to scale-up.
- 21 working days from enquiry
- 10–100 mg typical from 1 L
- Up to 10 L on request
Route 02
CHO & HEK expression
For proteins that need a mammalian cell to be themselves — glycosylation, complex disulfides, secretion. Transient, no stable line required.
- 31 working days from enquiry
- 50–300 mg typical for an IgG
- Serum-free suspension culture
| Capability | E. coli | CHO |
|---|---|---|
| Native N-glycosylation | —no | ●yes |
| Full-length IgG | —no | ●yes |
| Nanobodies, scFv, designed miniproteins | ●yes | —no |
| Cheapest route to a first answer | ●yes | —no |
How it works
Five stages, one date, no surprises in week three.
The schedule below is the one we quote against — and the third stage is the one that matters, because it is where a difficult target shows itself while changing course is still cheap.
Day 0
Quote and route advice
Days 1–8
Construct and cloning
Days 9–12
Expression test
Days 13–19
Culture and purification
Days 20–21
QC, then it ships
Why we built this
Making the protein is rarely the hard part. Waiting for it is.
Who this is for
Four kinds of team, one bottleneck
Teams designing proteins computationally
You generate candidates faster than you can test them. We close the loop: a design on Monday, real binding data a fortnight later.
Biotech and pharma R&D
You need material for the experiment in front of you, not in the next budget cycle — and without pulling your own people off their work.
Academic groups without expression capacity
You have the question but not the fermenters, the columns, or a spare pair of hands for six weeks.
Diagnostics and reagent developers
You need a defined antigen or enzyme in a reproducible batch, with the analytics to prove it is the same as last time.
Scope
What we will not take on.
A supplier who says yes to everything is telling you something about how the work will go. These are outside what we run, and we would rather point you somewhere better than learn it together at your expense.
- Insect cell / baculovirus expression
- Yeast (Pichia, S. cerevisiae) expression
- GMP or clinical-grade material
- Supply for diagnostic or therapeutic use
Batch pricing
Testing twenty designs should not cost twenty times one.
Most of what you pay for is standing the project up, not running each culture. So a panel is not twenty separate orders — it is one batch, and the per-protein price collapses accordingly.
€600
per protein
€11,995
batch total
−75%
vs. ordering singly
1 L E. coli per protein, all in: gene synthesis, culture, purification, QC and EU shipping. Mammalian panels follow the same principle and are quoted individually.
Questions
What people ask first
Do I need a plasmid, or is a sequence enough?
A sequence is enough. The 21 working days are counted from your enquiry and include codon optimisation, gene synthesis and cloning. If you already have a validated construct, it lands sooner.
What are the endotoxin levels?
On E. coli material, low as standard — measured and reported with the batch. It is how we work rather than an add-on, so bacterial material is normally ready for cell-based assays without a separate clean-up step. Endotoxin is a bacterial product, so it is not part of the standard QC panel on mammalian runs.
How much protein do I actually get?
10–100 mg from a standard 1 L E. coli culture for a well-behaved target, which is normally plenty for binding assays, structural work or a first functional test. Yield is target-dependent — we give you a realistic range in the quote rather than a number we cannot hit.
What if the protein does not express?
Some targets are simply hard, and we say so before taking the order rather than after. Where a target looks risky in the system you picked, we tell you what we would try instead, and we agree in writing what happens if it fails — before you commit.
Is this GMP material?
No. This is research-grade material for R&D use only. It is not for clinical, diagnostic or therapeutic use, and we do not supply it for those purposes.
What happens to my sequences?
They stay yours. We sign your NDA before you send anything, we do not reuse constructs across customers, and we do not retain material after a project closes unless you ask us to.
Send us a sequence.
A rough description and a deadline are enough to get a fixed price and a delivery date. We normally reply within one working day.